To vaccinate or not to vaccinate? Make your decision consciously

Added:2024-04-11

How the vaccine works

The mechanism of vaccination involves stimulating the body's immune system to produce an immune response against a given pathogen, such as a virus or bacterium, without the need for actual infection. This process uses the principle that the body can recognize and remember foreign molecules called antigens, which are characteristic of pathogens.

There are two main vaccination mechanisms:

  • vaccines with weakened or killed microorganisms
  • antigen- or protein-based vaccines; these may be fragments of a virus, bacteria or even synthetically produced antigens.

In both cases, when the body is vaccinated, its immune system responds by producing antibodies and immune memory cells. Memory cells remember the presence of the pathogen and remain in the body, ready to respond quickly if the infection reoccurs.

What does the vaccine contain?

Vaccines contain substances that are designed to deliver antigens and other ingredients that help stimulate the immune system. Here are some key ingredients:

  • antigens : pathogen-derived or synthetically produced molecules that are characteristic of a given pathogen. Antigens stimulate the immune system to react and create antibodies and immune cells that can fight the pathogen in the future;
  • adjuvants : substances added to vaccines to enhance and prolong the immune response. They help increase the effectiveness of the vaccine by increasing the production of antibodies and activating immune cells. Examples of adjuvants include aluminum compounds, silicates, and lipids;
  • stabilizing substances : help keep the vaccine stable during storage and transport; these may be sugars, amino acids, albumins or other substances;
  • preservatives : help prevent the growth of microorganisms in the preparation;
  • buffers : to maintain the appropriate pH and ensure the stability of the preparation;
  • emulsion stabilizing substances : help maintain the stability of the emulsion in the preparation.

Heavy metals in vaccines – fact or myth?

Most vaccines do not contain heavy metals as added ingredients, but they may be present in trace amounts as contaminants from manufacturing processes or ingredients used in production. Examples of heavy metals that may be present in vaccines include:

  • Mercury : Historically, mercury was used as a preservative in some vaccines, especially influenza. However, due to safety concerns, its use has been virtually eliminated and the amounts that may be present as contaminants are very low;
  • aluminum : may be present in some vaccines as an adjuvant. However, the amounts of aluminum in vaccines are small and generally considered safe;
  • iron : some vaccines, especially those against viruses, may contain traces of iron, which may come from the substances used in their production;
  • mercury: thiomersal, sodium salt of ethylmercurythiosalicylic acid, characterized by significant toxicity.

“Traces of heavy metals” may not sound dangerous, but how do you know how much of them you already have in your body? How much of them do you get from food and air every day? Can your detoxification organs handle their removal? How do you know whether they will react with other circulating substances in your body - after all, everyone is different? These and other unknowns are worth considering individually.

How does the body deal with the virus?

Contact of the body with the virus triggers a number of complex reactions in the immune system that are aimed at fighting and eliminating it. The process goes something like this:

  • virus detection : When a virus enters the body, the immune system detects the presence of foreign particles called viral antigens. Immune system cells, such as macrophages, are responsible for recognizing and capturing the virus,
  • activation of the immune response : when the virus is detected, the immune system activates its immune response. In antigen-presenting cells (for example, macrophages), viral antigens are presented to T lymphocytes, which are key players in the immune response,
  • production of antibodies : B lymphocytes become activated and begin to produce antibodies directed against viral antigens. Antibodies are proteins that bind to the virus and help neutralize it, e.g. by neutralization, agglutination (clumping) or activation of the complement system,
  • attack on infected cells : cytotoxic T lymphocytes (cytotoxic T lymphocytes) recognize infected cells, attack and destroy to prevent further spread of the virus,
  • cytokine secretion : immune cells secrete cytokines, which are signaling proteins that regulate the immune response. Cytokines help coordinate the actions of immune cells and enhance the response against the virus,
  • formation of immunological memory : after defeating the infection, some lymphocytes become immune memory cells that remain in the body and remember the virus antigen. This allows for a faster and more effective immune response in the event of repeated exposure to the same virus in the future.

Generally speaking, when exposed to a virus, the body triggers a complex series of processes to fight the infection and restore health. These actions require the cooperation of different cells and molecules of the immune system, which work together to provide protection against the virus.

What can help trigger an immune response?

  • balanced diet : eating a healthy and varied diet rich in fruits, vegetables, whole grains, healthy sources of protein and fats helps provide the body with the appropriate amount of nutrients necessary to support the immune system,
  • regular physical activity : regular physical activity helps strengthen the immune system by improving blood circulation and stimulating immune cells to act,
  • getting enough sleep : adequate sleep is crucial for the proper functioning of the immune system. Insufficient sleep can weaken our immunity,
  • avoiding stress : long-term stress can weaken our immunity, so it is worth using relaxation techniques such as meditation, yoga or deep breathing to reduce stress levels and improve the functioning of the immune system,
  • avoiding smoking and excessive alcohol consumption : stimulants weaken the immune system, so it is worth avoiding harmful substances.

The body's superheroes

The body has many defense reactions. If the body works efficiently and we provide it with appropriate conditions, it can easily cope with pathogenic microorganisms and the body's self-healing. The most important defenders of the body include:

  • Macrophages : Macrophages are cells that "patrol" the body, looking for foreign substances such as viruses and bacteria. Once they detect the virus, they can engulf it and destroy it. In an analogy to superheroes, they could be compared to vigilantes who discover the presence of a virus and prepare to fight.
  • B lymphocytes : B lymphocytes are cells that produce antibodies, i.e. proteins that can recognize and bind to viruses, which leads to their neutralization. In a superhero analogy, B cells are like sharpshooters who produce special "missiles" (antibodies) that can destroy the virus.
  • T lymphocytes : T lymphocytes perform various functions in the immune response, including identifying infected cells and helping to eliminate them. They can directly attack infected cells or emit signals that activate other immune cells to fight the virus. In a superhero analogy, T cells can be like commanders who direct the actions of other cells in the fight against the virus.
  • interferon: a group of proteins secreted by body cells in response to the presence of viruses, bacteria, parasites, tumors and other immunological stimuli; activates the enzyme RNAse L, which cuts the virus's RNA like scissors;
  • Natural Killer (NK) cells are a type of lymphocytes that play an important role in defending the body against infections and controlling the growth of cancer. They are part of the innate immune system and act quickly in response to infected cells and cancer cells, without the need for prior stimulation by antigens.       

mRNA vaccines

mRNA is used in modern vaccine technologies, such as COVID-19 vaccines, which use the genetic information of the SARS-CoV-2 virus to generate an immune response against the virus. mRNA is a key element in the gene expression process that allows cells to produce proteins necessary for various cellular functions, such as enzymes, hormones, receptors, and structural proteins. When a cell is infected by a virus, the mechanisms that detect the presence of the virus in the cell trigger a cascade of signals that lead to the activation of interferons, including type I interferons (alpha and beta interferons). These interferons, in turn, induce the expression of various genes, including the RNAse L gene. mRNA is one of the targets of RNAse L. RNAse L recognizes and degrades some specific mRNA sequences, which leads to the inhibition of the synthesis of proteins that are necessary for virus replication. Without mRNA, the virus is unable to produce the necessary proteins, which hinders its ability to spread within the host cell.

The enzyme RNAse L destroys the virus's mRNA

The RNAse L enzyme is an endoribonuclease, which means that it is an enzyme capable of cutting phosphodiester bonds inside RNA molecules. This enzyme is present in the cells of eukaryotic organisms and is associated with the process of RNA degradation. RNAse L plays an important role in the regulation of gene expression and in the body's immune response to viral infections by degrading viral RNA. Activation of RNAse L is one of the cell defense mechanisms in response to viral infection, which leads to the elimination of the virus by degradation of its RNA.

In practice, the RNAse L enzyme can be compared to "scissors" in the cell, which can cut special threads made of RNA, one of the genetic materials. RNAse L then begins to cut and destroy the virus's RNA, killing it, which helps the body fight the infection.

When may the autoimmune response fail?

There are many factors that can interfere with the immune response, leading to a weakened or dysfunctional immune system:

  • stress : long-term stress can lead to excessive production of stress hormones such as cortisol, which can weaken the immune system by reducing the activity of immune cells and reducing the body's ability to fight infections;
  • malnutrition : dietary deficiencies, especially deficiencies in nutrients such as vitamins and minerals, can weaken the immune system, leading to reduced production of immune cells and a lowered immune response to infections.
  • autoimmune diseases , in which the immune system attacks the body's own cells and tissues, can disrupt the normal function of the immune system, leading to overactivation or weakening of the immune response;
  • infections : some infections, especially those caused by viruses, can directly weaken the immune system, leading to a reduction in the number of immune cells and disruption of the functioning of the immune system;
  • aging : as we age, the immune system becomes less effective at fighting infections and responding to immune stimuli;
  • immunosuppressive drugs : some drugs, such as corticosteroids, chemotherapy and post-transplant drugs, can weaken the immune system by inhibiting the activity of immune cells,
  • environmental factors : exposure to toxins, environmental pollutants, UV radiation, exposure to intense magnetic fields from everyday devices, intake of large amounts of heavy metals, e.g. from food products, and other environmental factors may affect the immune system, weakening its function and increasing the risk infection.

How to deal with the virus without vaccination

Lifestyle, diet and the way our body functions are crucial for the functioning of our intestines, which in turn affects the immune system. The human body is equipped with a number of defense mechanisms, and only a neglected one with reduced immunity may have difficulty repelling an attack by an intruder. The proper balance of the microbiome is important for maintaining health, so during periods of increased viral infections, it is worth taking probiotics that will help maintain homeostasis. PoVir is a product that not only contains the beneficial and effective Narine bacterium, but also activates interferon - one of the body's defense shields - which in turn activates the enzyme RNAse L, which destroys the RNA of the virus. This is a unique product that accelerates and strengthens the body's natural defenses.

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The content presented is for informational purposes and does not replace medical treatment. They may be used by users solely at their own risk. We recommend consulting a doctor.