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Probiotics and Acne – A Holistic Approach to Treating Acne
Added:2023-11-23
The skin of the face is a unique calling card for every person. It is an image element defining the identity thanks to which we are unique and exceptional. Acne as a skin disease has a negative impact on well-being, often lowering self-esteem, especially since it most often appears in adolescence; a time full of contradictions, but also an intensive stage of building one's own identity, with exceptional sensitivity in shaping one's position in the peer group. Skin lesions are quite often treated as a superficial condition resulting from hormonal disorders. The cause, however, comes down to a common problem attributed to people in adolescence. This does not seem to be entirely correct, because quite often this condition appears after the age of 40. So why does it happen?
Acne – the terror of teenagers?
Acne vulgaris is an inflammatory skin disease characterized by the appearance of eruptions such as blackheads, spots, papules, and cysts. The most frequently cited factors causing this skin disease include:
• abnormal keratinization of the sebaceous ducts,
• bacterial colonization (Cutibacterium Acnes),
• increased sebum production,
• genotypic factors,
• hormonal disorders.
Due to the fact that many changes occur in the body of a young person, including in the hormonal system, and other factors such as stress or mood swings affect the well-being and functioning of a teenager, it is common to treat acne as a symbol of adolescence.
There are currently many studies related to this disease entity, which indicate a more complex problem, which does not have one specific cause, but rather is influenced by many interdependencies. In addition, the issue of adult acne is also increasingly common, because even people over 40 suffer from it, even if they did not have such a problem before.
Cutibacterium Acnes – is it the main “culprit” of acne?
The most likely pathogen of acne is considered to be the bacterium Cutibacterium acnes. It is most common in areas rich in sebum, such as the scalp, face, chest, and back.
It is worth mentioning that the skin microflora consists mainly of bacteria belonging to three types:
• Corynebacteria,
• Cutibacterium Acnes,
• Staphylococci.
The interplay between members of the skin microbiota is essential for maintaining healthy skin. Although C. acnes is dominant in sebaceous sites, it plays a key role in regulating skin homeostasis and preventing colonization by other harmful pathogens; in the case of acne vulgaris, it can also act as an opportunistic pathogen (microorganisms that cause infections only in immunocompromised individuals). New findings show that, contrary to what was previously thought, the presence of C. acnes itself is not the cause of acne, but rather an imbalance between members of the skin flora and between strains of this particular bacterium.
Studies have shown that acne skin does not harbor more C. acnes than normal skin; the relative abundance of this bacterium (in metagenomic studies) is similar in acne patients and healthy individuals (87–89%).1 Furthermore, it has been established that acne is caused not only by a specific strain of C. acnes but also by host and environmental factors that may potentially cause different levels of activation of innate immunity in severe acne. Furthermore, factors such as diet, stress, and the gut microbiome also influence the course, intensity, and duration of the disease.
How to support acne treatment with diet?
Studies show that there is a link between acne and the consumption of high glycemic index foods, which affect insulin levels. This hormone plays a key role in carbohydrate metabolism and regulates blood glucose levels. High insulin levels increase the production of growth hormone (GH), which in turn leads to an increase in the IGF-1 factor. Its increased level causes sebum production and the growth of sebaceous gland cells, and therefore contributes to the formation of acne lesions.
One of the first studies on dietary intervention in the treatment of acne vulgaris was conducted in 2007 by Smith et al. 43 men aged 15–25 with moderate acne received meals with a low glycemic load for 12 weeks. After this time, the number of acne lesions, levels of sex hormones and insulin markers were compared with those at the beginning of treatment. The study showed significant improvement in the occurrence and course of acne2. This shows that changing the diet and eating habits can have a beneficial and supportive effect on the treatment of skin lesions. In addition, a diet rich in simple sugars and highly processed foods disrupts the work of the intestines and, consequently, affects the quality of the skin, as the existence of the gut-skin axis has been proven.
Guts and Acne: What's the Connection?
Both acne and the condition of the digestive tract are related to the quality of the gut microbiome. The skin and intestines are very densely vascularized and innervated; they perform neuroendocrine and immune functions, among others.
More and more studies indicate the interdependence of these two organs. Russian scientists, who studied 114 patients with acne vulgaris, noticed that 54% of acne patients had differences in their intestinal flora. In addition, they found that giving probiotics to patients with acne and intestinal dysbiosis shortened the duration of treatment3.
The existence of the gut-skin axis is evidenced by many elements. In addition to acting through the immune system, metabolic products and microbial compounds can affect the intestinal epithelium, changing their physiology. As a result, this leads to the creation of various secretory products, circulating throughout the body, also reaching the skin. Therefore, chemical compounds delivered with food can have an immediate effect on the appearance and quality of the skin.
The mechanism of acne treatment is also worth noting, as it is mainly based on the use of antibiotics, creating a vicious circle, because the commonly used treatment can actually eliminate the symptoms of acne, but it also causes a lot of negative side effects in the body. The use of oral antibiotic therapy destroys the bacterial flora of the digestive system, weakens the intestines, and also kills good bacteria. This creates a closed circle of mutual dependencies, in which the chosen solution helps with one, but damages the other. So is there a proven, effective way to deal with skin problems?
How to get rid of acne?
The beneficial effects of lactic acid bacteria, which normally inhabit the intestines, in treating acne were already appreciated in the 1930s, when doctors used oral supplementation of Lactobacillus acidophilus for this condition. In 1961, a study was conducted in which patients were given a probiotic for 16 days, with a two-week break after the first eight days. In 80% of acne patients, the appearance of their skin improved, with the most noticeable improvement in those with severe inflammatory acne.
In addition, oral probiotics have been shown to reduce inflammation and oxidative stress. They can also change the microbial community in places outside the digestive tract, which in turn can affect skin condition and acne.4 Studies show that taking probiotics can reduce skin eruptions. In addition, it has a positive effect on the intestinal microflora responsible for immunity, which plays a key role in fighting pathogenic conditions in the human body.
Which acne-fighting probiotic should you choose?
The probiotic should contain live cultures of Lactobacillus acidophilus bacteria. A wide range of probiotic supplements is available on the pharmaceutical and cosmetic market (also in this field the benefits of using probiotics are beginning to be appreciated).
It is worth paying attention to the viability of a given strain. Lactobacillus acidophilus Er-2 strain 317/402 Narine during clinical trials shows high effectiveness, because it is resistant to stomach acids and as a result reaches the intestines, settling on its walls.
It is important to remember that properly cared for intestinal microflora has a number of benefits, including facilitating the absorption of vitamins and microelements that are necessary, for example, to maintain the proper condition of the skin.
This means that using a probiotic with the Narine bacteria also increases the effect of other supplements, e.g. vitamins, through significantly better absorption.
Holistic Acne Treatment
1. Detoxification.
Regular cleansing of the body is essential to maintaining internal balance.
Narum OFFToxic forte is a combination of tansy and clove extract with a metabiotic.
Dosage: for the first week (7 days): 1 capsule, 2 times a day.
For the next 2 weeks (14 days): 2 capsules, 2 times daily.
Detox is a composition of 20 freeze-dried products supporting intestinal microflora. Take 2 capsules, 2 times a day.
The two preparations should be taken together. For optimal effect, it is recommended to use the products for at least 21 days. The set helps cleanse the body, regain energy and better well-being.
2. Rebuilding the intestinal bacterial flora.
Probiotics with Narine bacteria are highly effective in rebuilding intestinal flora. Narum Fast contains Narine bacteria and a metabiotic, while Narum forte contains non-pathogenic E.coli bacteria.
Use:
Stage I: Narum Fast until the end of the packages,
Stage II: Narum Forte until the end of the packages,
Stage III: Narum Plus until the end of the packages.
Dosage for adults and children over 12 years of age:
• Narum Fast - 2 capsules 3 times a day, 15-20 minutes before a meal,
• Narum Forte - 2 capsules 3 times a day, 15-20 minutes before a meal,
• Narum Plus - 2 capsules 3 times a day, 15-20 minutes before a meal.
3. Micro and macro elements.
Strengthening the body and taking care of the skin will be provided by White Mumio Acidophile . Far Eastern medicine indicates the beneficial effects of white mumio and support in caring for beautiful skin. White Mumio is micro and macro elements, the bacterium Lactobacterium mazuni "Karine" Str.2 and high absorption of the acidophilic form.
Receiving:
• adults and children over 6 years of age: 1-2 capsules 2 times a day,
• children from 3 to 6 years of age: 1 capsule 2 times a day (after dissolving in a drink).
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Bibliography:
1. Cutibacterium acnes ( Propionibacterium acnes ) and acne vulgaris: a brief look at the latest updates B. Dréno, S. Pecastaings, S. Corvec, S. Veraldiego, A. Khammari, C. Roquesa, 2018.
2,3,4 Edible Plants and Their Impact on the Gut Microbiome and Acne Ashley K. Clark, Kelly N. Haas, and Raja K. Sivamani, 2017.
Microbiome and probiotics in acne vulgaris—a narrative review, Karolina Chilicka, Iwona Dzieńdziora-Urbińska, Renata Szyguła, Binnaz Asanova and Danuta Nowicka March 2022.
Skin microbiome and the gut-cutaneous axis, Shivani Sinha MS ,Gloria Lin MS, 2021.
Impact of Gut Microbiome on Skin Health: Gut-Skin Axis Observed Through the Prism of Skin Therapy and Diseases Ms. Rayhan Mahmud , Sharmin Akter , Sanjida Khanam Tamanna , Lincon Mazumder , Israt Zahan Esti , Sanchita Banerjee , Sumona Akter , Md. Rakibul Hasan , Mrityunjoy Acharjee , Md. Sajjad Hossain and Anna Maria Pirttilä , 2022.
Probiotics in Acne Skin Care. A Review of the Latest Scientific Reports, Natalia Kurkowska 2021.
The impact of intestinal microbiota disorders on the occurrence of skin diseases, Marta Janoska, 2022.